Spain, the main gateway for drugs into the European Union, is immersed in a daily battle where various police, judicial, and medical forces engage in an unrelenting fight in this endless war against drug trafficking. The country faces constant challenges at its borders and strategic points. Divided on multiple fronts, law enforcement officers strive to curb the flow of illegal substances, customs laboratories work tirelessly analyzing evidence, and healthcare professionals try to mitigate the dangers faced by ‘The Mules.’ All of this to address the complexities of this never-ending war against drug trafficking.